1,3-Diphenyl-2-propenone - CAS 94-41-7
Catalog: |
BB041308 |
Product Name: |
1,3-Diphenyl-2-propenone |
CAS: |
94-41-7 |
Synonyms: |
0 |
IUPAC Name: | (E)-1,3-diphenylprop-2-en-1-one |
Description: | 1,3-Diphenyl-2-propenone (CAS# 94-41-7) is used in the preparation of pharmacologically-interesting heterocyclic systems like pyrazolines and pyrimidines. It also inhibits the proliferation of human breast cancer cell lines, MCF-7 and MDA-MB-231 by inducing apoptosis and blocking cell cycle progression in the G2/M phase. |
Molecular Weight: | 208.26 |
Molecular Formula: | 0 |
Canonical SMILES: | 0 |
InChI: | 0 |
InChI Key: | 0 |
Boiling Point: | 208 °C25 mmHg (lit.) |
Melting Point: | 55-59 °C |
Purity: | 97 % |
Solubility: | 92.93 mg/L at 25 °C (est) |
Appearance: | Light yellow powder |
MDL: | MFCD00003082 |
LogP: | 3.58270 |
Vapor Pressure: | 0.000107 [mmHg] |
GHS Hazard Statement: | H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] |
Precautionary Statement: | P261, P264, P270, P271, P280, P301+P312, P304+P340, P305+P351+P338, P312, P330, P337+P313, P403+P233, P405, and P501 |
Signal Word: | Warning |
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PMID | Publication Date | Title | Journal |
32705535 | 20201201 | Hydroxysafflor Yellow A of Carthamus Tinctorius L., Represses the Malignant Development of Esophageal Cancer Cells via Regulating NF-κB Signaling Pathway | Cell biochemistry and biophysics |
32986415 | 20201116 | 6-Prenylnaringenin from Hops Disrupts ERα-Mediated Downregulation of CYP1A1 to Facilitate Estrogen Detoxification | Chemical research in toxicology |
31299238 | 20190901 | Artocarmitin B enhances intracellular antioxidant capacity via activation of Nrf2 signaling pathway in human lung epithelial cells | Chemico-biological interactions |
30890322 | 20190501 | Isobavachalcone reveals novel characteristics of methuosis-like cell death in leukemia cells | Chemico-biological interactions |
30608650 | 20190218 | The Multiple Biological Targets of Hops and Bioactive Compounds | Chemical research in toxicology |
Complexity: | 242 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 1 |
Exact Mass: | 208.088815002 |
Formal Charge: | 0 |
Heavy Atom Count: | 16 |
Hydrogen Bond Acceptor Count: | 1 |
Hydrogen Bond Donor Count: | 0 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 208.088815002 |
Rotatable Bond Count: | 3 |
Topological Polar Surface Area: | 17.1 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 3.1 |
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