1-(2-Propyn-1-yl)cyclobutanol - CAS 37418-60-3
Catalog: |
BB076601 |
Product Name: |
1-(2-Propyn-1-yl)cyclobutanol |
CAS: |
37418-60-3 |
Synonyms: |
1-(2-Propynyl)cyclobutanol |
IUPAC Name: | 1-prop-2-ynylcyclobutan-1-ol |
Description: | 1-(2-Propyn-1-yl)cyclobutanol is used as a reactant in the preparation of condensed pyrimidine compounds as RET inhibitors. |
Molecular Weight: | 110.15 |
Molecular Formula: | C7H10O |
Canonical SMILES: | C#CCC1(CCC1)O |
InChI: | InChI=1S/C7H10O/c1-2-4-7(8)5-3-6-7/h1,8H,3-6H2 |
InChI Key: | SGEZRFWQVYNBRJ-UHFFFAOYSA-N |
References: | Miyazaki, Isao, et al. PCT Int. Appl., WO 2017043550 A1 20170316 (2017). |
Complexity: | 125 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 110.073164938 |
Formal Charge: | 0 |
Heavy Atom Count: | 8 |
Hydrogen Bond Acceptor Count: | 1 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 110.073164938 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 20.2Ų |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 0.8 |
-
Catalog: BB067784
((1R,2R)-2-(2,3-Dihydrobenzofuran-4-yl)cyclopropyl)methanamine
Detail
-
Catalog: BB064244
((2S,3R)-4-(4-(((((3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl)oxy)carbonyl)amino)-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamic Acid Phenylmethyl Ester
Detail
-
Catalog: BB074213
((2R,3S,4R,5R,6R)-5-Acetamido-3,4-dihydroxy-6-(2-(trimethylsilyl)ethoxy)tetrahydro-2H-pyran-2-yl)methyl 4-Methylbenzenesulfonate
Detail
-
Catalog: BB069173
((1-Chloro-2-methylpropan-2-yl)oxy)trimethylsilane
Detail
-
Catalog: BB074488
((1R,3R)-3-Amino-cyclopentyl)-carbamic Acid tert-Butyl Ester
Detail
-
Catalog: BB071775
((1R,4R)-4-(((tert-butyldimethylsilyl)oxy)methyl)cyclohexyl)methanol
Detail
-
Catalog: BB061033
((2R,5S,10aS,10bS)-10b-Hydroxy-5-isopropyl-2-methyl-3,6-dioxooctahydro-2H-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl)carbamic Acid Benzyl Ester
Detail
-
Catalog: BB069928
((2S,4R)-2-(Chloromethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl 4-Methylbenzenesulfonate
Detail
Online Inquiry
Customer Support
Customer Centered
Related Functional Groups
Other Building Blocks
Customers Also Viewed
INDUSTRY LEADERS TRUST OUR PRODUCTS