1-(2-Methoxyphenyl)cyclopropanecarboxylic Acid - CAS 74205-24-6
Catalog: |
BB035022 |
Product Name: |
1-(2-Methoxyphenyl)cyclopropanecarboxylic Acid |
CAS: |
74205-24-6 |
Synonyms: |
1-(2-methoxyphenyl)-1-cyclopropanecarboxylic acid; 1-(2-methoxyphenyl)cyclopropane-1-carboxylic acid |
IUPAC Name: | 1-(2-methoxyphenyl)cyclopropane-1-carboxylic acid |
Description: | 1-(2-Methoxyphenyl)cyclopropanecarboxylic Acid (CAS# 74205-24-6) is used as a reactant in the preparation of N-pyridinyl carboxamide derivatives as modulators of atp-binding CASsette transporters. |
Molecular Weight: | 192.21 |
Molecular Formula: | C11H12O3 |
Canonical SMILES: | COC1=CC=CC=C1C2(CC2)C(=O)O |
InChI: | InChI=1S/C11H12O3/c1-14-9-5-3-2-4-8(9)11(6-7-11)10(12)13/h2-5H,6-7H2,1H3,(H,12,13) |
InChI Key: | CZPYUTXQDVNAFL-UHFFFAOYSA-N |
MDL: | MFCD00297169 |
LogP: | 1.81140 |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
JP-2019514840-A | Modulator of cystic fibrosis transmembrane conductance regulator protein | 20160426 |
US-10118916-B2 | Modulators of cystic fibrosis transmembrane conductance regulator protein | 20160426 |
US-2017305891-A1 | Modulators of cystic fibrosis transmembrane conductance regulator protein | 20160426 |
WO-2017187321-A1 | Modulators of cystic fibrosis transmembrane conductance regulator protein | 20160426 |
US-2011098311-A1 | Compositions for treatment of cystic fibrosis and other chronic diseases | 20091022 |
Complexity: | 233 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 192.078644241 |
Formal Charge: | 0 |
Heavy Atom Count: | 14 |
Hydrogen Bond Acceptor Count: | 3 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 192.078644241 |
Rotatable Bond Count: | 3 |
Topological Polar Surface Area: | 46.5 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 1.7 |
Online Inquiry
Customer Support
Customer Centered
Related Functional Groups
Carbonyl Compounds
Customers Also Viewed
INDUSTRY LEADERS TRUST OUR PRODUCTS