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| Description: | 1,2-Dihydroxyethyl-4-methylphenyl-tetrahydrofuran-3,4-diol is an intermediate in the synthesis of 1-C-[3-[[5-(4-Fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-D-glucose (F594031), an intermediate used in the synthesis of Canagliflozin (C175190). Canagliflozin is a sodium/glucose cotransporter 2 (SGLT2) inhibitor; Canagliflozin is a candidate for the treatment of type 2 diabetes and obesity. |
| Molecular Weight: | 444.52 |
| Molecular Formula: | C24H25FO5S |
| References: | Metil, D. S., et al: Org. Process Res. Dev., 22, 27 (2018); Chao, E. et al. Drug Fut., 36, 351 (2011); Sha, S. et al. Diab. Obes. Metab., 13, 669 (2011); Kipnes, M.S. Clin. Invest., 1, 145 (2011). |
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