1,2-Bis(trimethylsiloxy)cyclobutene - CAS 17082-61-0

Name: 1,2-Bis(trimethylsiloxy)cyclobutene
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog:	BB012674
Product Name:	1,2-Bis(trimethylsiloxy)cyclobutene
CAS:	17082-61-0
Synonyms:	trimethyl-(2-trimethylsilyloxycyclobuten-1-yl)oxysilane

Technical Data

IUPAC Name:	trimethyl-(2-trimethylsilyloxycyclobuten-1-yl)oxysilane
Description:	1,2-Bis(trimethylsiloxy)cyclobutene (CAS# 17082-61-0) is a useful chemical reactant used in the preparation and biological activity of serine and threonine β-lactones as inhibitors of hepatitis A virus 3C cysteine proteinase.
Molecular Weight:	230.45
Molecular Formula:	C10H22O2Si2
Canonical SMILES:	C[Si](C)(C)OC1=C(CC1)O[Si](C)(C)C
InChI:	InChI=1S/C10H22O2Si2/c1-13(2,3)11-9-7-8-10(9)12-14(4,5)6/h7-8H2,1-6H3
InChI Key:	WOBRFSDEZREQAB-UHFFFAOYSA-N
Boiling Point:	58-59 °C / 2 mmHg (lit.)
Density:	0.897 g/mL at 25 °C(lit.)
Appearance:	Colorless liquid
MDL:	MFCD00010798
LogP:	3.69480

GHS Hazard Statement:	H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
Precautionary Statement:	P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501
Signal Word:	Warning

Publication Number	Title	Priority Date
CN-113130998-A	Electrolyte flame-retardant additive and lithium ion battery electrolyte containing same	20210330
CA-3085255-A1	Eif4e-inhibiting compounds and methods	20190702
WO-2021003157-A1	Eif4e-inhibiting 4-oxo-3,4-dihydropyrido[3,4-d]pyrimidine compounds	20190702
WO-2020112706-A1	7-, 8-, and 10-SUBSTITUTED AMINO TRIAZOLO QUINAZOLINE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS, PHARMACEUTICAL COMPOSITIONS AND THEIR USE	20181130
CN-113166158-A	7-, 8-and 10-substituted aminotriazoloquinazoline derivatives as adenosine receptor antagonists, pharmaceutical compositions and uses thereof	20181130

PMID	Publication Date	Title	Journal
21175153	20110204	Synthesis of phantasmidine	Organic letters
17715931	20070913	Synthesis and ring expansions of functionalized spirocyclobutanones	Organic letters
16388658	20060106	Reactions of 1,2-bis(trimethylsilyloxy)cycloalkenes with the diethyl acetals of aldehydes	The Journal of organic chemistry

Complexity:	220
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	0
Exact Mass:	230.11583301
Formal Charge:	0
Heavy Atom Count:	14
Hydrogen Bond Acceptor Count:	2
Hydrogen Bond Donor Count:	0
Isotope Atom Count:	0
Monoisotopic Mass:	230.11583301
Rotatable Bond Count:	4
Topological Polar Surface Area:	18.5 Å²
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0