1-(2,2-Difluoroethyl)pyrazol-4-amine - CAS 1006333-08-9
Catalog: |
BB000276 |
Product Name: |
1-(2,2-Difluoroethyl)pyrazol-4-amine |
CAS: |
1006333-08-9 |
Synonyms: |
1-(2,2-difluoroethyl)-4-pyrazolamine; 1-(2,2-difluoroethyl)pyrazol-4-amine |
IUPAC Name: | 1-(2,2-difluoroethyl)pyrazol-4-amine |
Description: | 1-(2,2-Difluoroethyl)-1H-pyrazol-4-amine acts as a reagent for the development of pyrimidine derivatives as JAK3 inhibitors. |
Molecular Weight: | 147.13 |
Molecular Formula: | C5H7F2N3 |
Canonical SMILES: | C1=C(C=NN1CC(F)F)N |
InChI: | InChI=1S/C5H7F2N3/c6-5(7)3-10-2-4(8)1-9-10/h1-2,5H,3,8H2 |
InChI Key: | LMAYRTOWGOVCOR-UHFFFAOYSA-N |
Storage: | Keep in dark place, Inert atmosphere, 2-8 °C |
LogP: | 1.31160 |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
AU-2018394995-A1 | Amino-fluoropiperidine derivative as kinase inhibitor | 20171228 |
AU-2018394996-A1 | Amino-methyl piperidine derivative as kinase inhibitor | 20171228 |
AU-2018394997-A1 | Oxy-fluoropiperidine derivative as kinase inhibitor | 20171228 |
KR-20190080540-A | Amino-fluoropiperidine derivatives as kinase inhibitor | 20171228 |
KR-20190080541-A | Amino-methylpiperidine derivatives as kinase inhibitor | 20171228 |
Complexity: | 109 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 147.06080356 |
Formal Charge: | 0 |
Heavy Atom Count: | 10 |
Hydrogen Bond Acceptor Count: | 4 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 147.06080356 |
Rotatable Bond Count: | 2 |
Topological Polar Surface Area: | 43.8 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 0.3 |
-
Catalog: BB044292
(+)-(8,8-Dichlorocamphorylsulfonyl)oxaziridine
Detail
-
Catalog: BB051699
(1-(2,2-Difluoroethyl)-1H-pyrazol-4-yl)methanamine hydrochloride
Detail
-
Catalog: BB044156
(-)-2,10-(3,3-dichlorocamphorsultam)
Detail
-
Catalog: BB053726
(±)-Dihydrozeatin
Detail
-
Catalog: BB043168
(+/-)-3-Amino-1,2,3,4-tetrahydroquinoline
Detail
-
Catalog: BB053081
({1-[(1,5-Dimethyl-1H-Pyrazol-4-Yl)Methyl]Piperidin-3-Yl}Methyl)Amine Dihydrochloride
Detail
-
Catalog: BB043409
(+/-)-2-Amino-2-desoxy-3-O-hexadecyl-glycerol
Detail
-
Catalog: BB019528
(1alpha,5alpha,6alpha)-6-Amino-3-Boc-3-azabicyclo[3.1.0]hexane
Detail
Online Inquiry
Customer Support
Customer Centered
Related Functional Groups
Amines and Anilines
Customers Also Viewed
INDUSTRY LEADERS TRUST OUR PRODUCTS