5-Methyl-2'-O,4'-C-methyleneuridine - CAS 206055-67-6
Catalog: |
BB016097 |
Product Name: |
5-Methyl-2'-O,4'-C-methyleneuridine |
CAS: |
206055-67-6 |
Synonyms: |
LNA-5MeU; 1-[(1S,3R,4R,7S)-7-Hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-5-methylpyrimidine-2,4(1H,3H)-dione; 1-(2'-O-4-C-Methylene-b-D-ribofuranosyl)thymine; 1-[2,5-Anhydro-4-(hydroxymethyl)-α-L-lyxofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione |
IUPAC Name: | 1-[(1S,3R,4R,7S)-7-hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-5-methylpyrimidine-2,4-dione |
Description: | 5-Methyl-2'-O,4'-C-methyleneuridine (CAS# 206055-67-6 ) is a useful research chemical. |
Molecular Weight: | 270.24 |
Molecular Formula: | C11H14N2O6 |
Canonical SMILES: | CC1=CN(C(=O)NC1=O)C2C3C(C(O2)(CO3)CO)O |
InChI: | InChI=1S/C11H14N2O6/c1-5-2-13(10(17)12-8(5)16)9-6-7(15)11(3-14,19-9)4-18-6/h2,6-7,9,14-15H,3-4H2,1H3,(H,12,16,17)/t6-,7+,9-,11+/m1/s1 |
InChI Key: | TYYUAZVXLRMUMN-SZVQBCOZSA-N |
Melting Point: | 196-198 ℃ |
Purity: | ≥ 95 % |
Density: | 1.598±0.1 g/cm3 (Predicted) |
Appearance: | White to light brown powder |
Storage: | Store at 2-8 ℃ |
LogP: | -2.13540 |
GHS Hazard Statement: | H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] |
Precautionary Statement: | P264, P270, P301+P317, P330, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
US-2021277392-A1 | Chemically-modified guide rnas to improve crispr-cas protein specificity | 20171102 |
WO-2017184082-A1 | A lymphocyte permeating chimeric oligonucleotide, methods and uses thereof | 20160422 |
EP-2899197-A1 | Olgionucleotide and artificial nucleoside having guanidine bridge | 20120921 |
EP-2899197-B1 | Oligonucleotide and artificial nucleoside having guanidine bridge | 20120921 |
ES-2622716-T3 | Oligonucleotide and artificial nucleoside in bridge with guanidine | 20120921 |
Complexity: | 478 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 4 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 270.08518617 |
Formal Charge: | 0 |
Heavy Atom Count: | 19 |
Hydrogen Bond Acceptor Count: | 6 |
Hydrogen Bond Donor Count: | 3 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 270.08518617 |
Rotatable Bond Count: | 2 |
Topological Polar Surface Area: | 108 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | -1.8 |
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