1-(1-Methyl-4-piperidyl)pyrazole-4-boronic Acid Pinacol Ester - CAS 1323919-64-7
Catalog: |
BB007582 |
Product Name: |
1-(1-Methyl-4-piperidyl)pyrazole-4-boronic Acid Pinacol Ester |
CAS: |
1323919-64-7 |
Synonyms: |
1-methyl-4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-pyrazolyl]piperidine; 1-methyl-4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazol-1-yl]piperidine |
IUPAC Name: | 1-methyl-4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazol-1-yl]piperidine |
Description: | 1-(1-Methyl-4-piperidyl)pyrazole-4-boronic Acid Pinacol Ester (CAS# 1323919-64-7) is used in the synthesis of a series of hydroxybenzoxazole derivatives as c-Met kinase inhibitors. |
Molecular Weight: | 291.20 |
Molecular Formula: | C15H26N3O2B |
Canonical SMILES: | B1(OC(C(O1)(C)C)(C)C)C2=CN(N=C2)C3CCN(CC3)C |
InChI: | InChI=1S/C15H26BN3O2/c1-14(2)15(3,4)21-16(20-14)12-10-17-19(11-12)13-6-8-18(5)9-7-13/h10-11,13H,6-9H2,1-5H3 |
InChI Key: | PRLTVODJPCFDHW-UHFFFAOYSA-N |
Storage: | Sealed in dry, 2-8 °C |
LogP: | 1.38690 |
Publication Number | Title | Priority Date |
US-2021171535-A1 | Tricyclic heterocycles as fgfr inhibitors | 20191204 |
WO-2021113479-A1 | Tricyclic heterocycles as fgfr inhibitors | 20191204 |
US-2021115053-A1 | Bicyclic heterocycles as fgfr inhibitors | 20191016 |
WO-2021076728-A1 | Bicyclic heterocycles as fgfr inhibitors | 20191016 |
US-2021094935-A1 | Bicyclic heterocycles as fgfr inhibitors | 20191001 |
Complexity: | 367 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 291.2118072 |
Formal Charge: | 0 |
Heavy Atom Count: | 21 |
Hydrogen Bond Acceptor Count: | 4 |
Hydrogen Bond Donor Count: | 0 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 291.2118072 |
Rotatable Bond Count: | 2 |
Topological Polar Surface Area: | 39.5 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
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