1,1-Dimethylbiguanide hydrochloride - CAS 1115-70-4
Catalog: |
BB002779 |
Product Name: |
1,1-Dimethylbiguanide hydrochloride |
CAS: |
1115-70-4 |
Synonyms: |
Imidodicarbonimidic diamide, N,N-dimethyl-, hydrochloride (1:1); Biguanide, 1,1-dimethyl-, hydrochloride; Biguanide, 1,1-dimethyl-, monohydrochloride; Imidodicarbonimidic diamide, N,N-dimethyl-, monohydrochloride; Apo-Metformin; Apophage; Benofomin; Brot; Dabex; Denkaform; Fornidd; Geamet; Glifage; LA 6023; Meguan; Metformin hydrochloride; N,N-Dimethylbiguanide hydrochloride; N1,N1-Dimethylbiguanide hydrochloride; Nelbis; Neodipa; Obimat-SR; Orabet; Riomet; Siamformet; Walaphage |
Ordering Information
Catalog |
Size |
Price |
Stock |
BB002779 |
500 g |
$199 |
In stock |
Related CAS: | 15537-72-1 (Deleted CAS) 56258-19-6 (Deleted CAS) 144377-16-2 (Deleted CAS) 657-24-9 (free base)
|
IUPAC Name: | 3-(diaminomethylidene)-1,1-dimethylguanidine;hydrochloride |
Description: | 1,1-Dimethylbiguanide hydrochloride is the hydrochloride salt of the biguanide metformin with antihyperglycemic and potential antineoplastic activities. It decreases hyperglycemia primarily by suppressing glucose production by the liver (hepatic gluconeogenesis). |
Molecular Weight: | 165.62 |
Molecular Formula: | C4H12ClN5 |
Canonical SMILES: | CN(C)C(=N)N=C(N)N.Cl |
InChI: | InChI=1S/C4H11N5.ClH/c1-9(2)4(7)8-3(5)6;/h1-2H3,(H5,5,6,7,8);1H |
InChI Key: | OETHQSJEHLVLGH-UHFFFAOYSA-N |
Boiling Point: | 224.1±50.0°C at 760 mmHg |
Melting Point: | 232°C |
Purity: | ≥95% |
Solubility: | Soluble in DMSO (Slightly), Methanol (Slightly) |
Appearance: | White crystalline powder |
Storage: | Store at -20°C |
Decomposition: | Hazardous decomposition products formed under fire conditions - carbon oxides, Nitrogen oxides (nox), Hydrogen chloride gas. /metformin hydrochloride/ |
MDL: | MFCD00012582 |
LogP: | 1.05850 |
Quality Standard: | BP\EP\USP |
Stability: | Stable under recommended storage conditions. /metformin hydrochloride/ |
Vapor Pressure: | 7.58X10-5 mm Hg at 25 °C (est) |
GHS Hazard Statement: | H302 (99.62%): Harmful if swallowed [Warning Acute toxicity, oral] |
Precautionary Statement: | P261, P264, P270, P271, P273, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
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PMID | Publication Date | Title | Journal |
34058177 | 20210825 | Metformin impairs bile acid homeostasis in ethinylestradiol-induced cholestasis in mice | Chemico-biological interactions |
33844015 | 20210716 | Perfluorooctanesulfonic Acid (PFOS) Thwarts the Beneficial Effects of Calorie Restriction and Metformin | Toxicological sciences : an official journal of the Society of Toxicology |
33823243 | 20210601 | Vanillin exerts therapeutic effects against hyperglycemia-altered glucose metabolism and purinergic activities in testicular tissues of diabetic rats | Reproductive toxicology (Elmsford, N.Y.) |
33147367 | 20210301 | Cytotoxicity of metformin against HT29 colon cancer cells contributes to mitochondrial Sirt3 upregulation | Journal of biochemical and molecular toxicology |
33476677 | 20210301 | Metformin relieves H/R-induced cardiomyocyte injury through miR-19a/ACSL axis - possible therapeutic target for myocardial I/R injury | Toxicology and applied pharmacology |
Complexity: | 132 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 2 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 165.0781231 |
Formal Charge: | 0 |
Heavy Atom Count: | 10 |
Hydrogen Bond Acceptor Count: | 1 |
Hydrogen Bond Donor Count: | 4 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 165.0781231 |
Rotatable Bond Count: | 2 |
Topological Polar Surface Area: | 91.5 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
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