Description: | 1,1-Diethoxypropan-2-one Oxime is an intermediate for the synthesis of Nilotinib 3-Imidazolyl N-oxide (M326296), which is an impurity compound of Nilotinib (N465300), useful in the treatment of chronic myelogenous leukemia. |
Molecular Weight: | 161.2 |
Molecular Formula: | C7H15NO3 |
Solubility: | Chloroform; Dichloromethane; Diethyl Ether; Methanol |
Appearance: | Colorless Oil |
References: | Wei-Sheng H., et al. Synthesis, 14, 2121 (2007); Corbin, A., et al. J. Biol. Chem., 277, 32214(2002), Golemovic, M., et al. Clin. Cancer Res., 11, 4941 (2005), Gleixner, K., et al. Blood, 107, 752 (2006), Nicolini, F., et al. Leukemia, 20, 1061 (2006),. |
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