1-[1-(4-Chlorophenyl)cyclobutyl]-3-methyl-1-butylamine - CAS 84467-54-9
Catalog: |
BB037207 |
Product Name: |
1-[1-(4-Chlorophenyl)cyclobutyl]-3-methyl-1-butylamine |
CAS: |
84467-54-9 |
Synonyms: |
1-[1-(4-chlorophenyl)cyclobutyl]-3-methyl-1-butanamine; 1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutan-1-amine |
IUPAC Name: | 1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutan-1-amine |
Description: | A metabolite of Sibutramine, a serotonin and noradrenaline reuptake inhibitor (SNR). Decreases calorie intake and increases energy expenditure. |
Molecular Weight: | 251.79 |
Molecular Formula: | C15H22ClN |
Canonical SMILES: | CC(C)CC(C1(CCC1)C2=CC=C(C=C2)Cl)N |
InChI: | InChI=1S/C15H22ClN/c1-11(2)10-14(17)15(8-3-9-15)12-4-6-13(16)7-5-12/h4-7,11,14H,3,8-10,17H2,1-2H3 |
InChI Key: | WQSACWZKKZPCHN-UHFFFAOYSA-N |
Boiling Point: | 337.9 °C at 760 mmHg |
Density: | 1.072 g/cm3 |
LogP: | 4.83540 |
Publication Number | Title | Priority Date |
CN-109738565-B | Method for determining illegally added compounds in health food | 20190131 |
TW-201534307-A | Method for treating behavioral and/or psychological abnormalities | 20130425 |
WO-2014176460-A1 | Methods of treating behaviorial and/or mental disorders | 20130425 |
AU-2014227807-A1 | Pharmaceutical composition comprising an AMPK activator and a serotonergic agent and methods of use thereof | 20130315 |
AU-2014227807-B2 | Pharmaceutical composition comprising an AMPK activator and a serotonergic agent and methods of use thereof | 20130315 |
PMID | Publication Date | Title | Journal |
27838152 | 20170101 | Sibutramine provokes apoptosis of aortic endothelial cells through altered production of reactive oxygen and nitrogen species | Toxicology and applied pharmacology |
24038852 | 20131201 | Effects of oral anorexiant sibutramine on the expression of cytochromes P450s in human hepatocytes and cancer cell lines | Journal of biochemical and molecular toxicology |
23777987 | 20130905 | Potent inhibition of cytochrome P450 2B6 by sibutramine in human liver microsomes | Chemico-biological interactions |
22902504 | 20121201 | Qualitative screening for adulterants in weight-loss supplements by ion mobility spectrometry | Journal of pharmaceutical and biomedical analysis |
22539020 | 20121101 | Short-term effects of sibutramine on mineral status and selected biochemical parameters in obese women | Biological trace element research |
Complexity: | 239 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 251.1440774 |
Formal Charge: | 0 |
Heavy Atom Count: | 17 |
Hydrogen Bond Acceptor Count: | 1 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 251.1440774 |
Rotatable Bond Count: | 4 |
Topological Polar Surface Area: | 26 |
Undefined Atom Stereocenter Count: | 1 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 4.5 |
Online Inquiry
Customer Support
Customer Centered
Related Functional Groups
Halides
Customers Also Viewed
INDUSTRY LEADERS TRUST OUR PRODUCTS